Elsevier

Resuscitation

Volume 24, Issue 2, November 1992, Pages 111-121
Resuscitation

Guidelines for advanced life support: A statement by the Advanced Life Support Working Party of the European Resuscitation Council, 1992

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      These data reflect evidence from randomised controlled trials that cardiac arrest drugs are effective in achieving ROSC and observational data showing a strong association between time to ROSC and functional outcome.11,13,20–22 Since the first resuscitation guidelines were published in 1974, the IV route has been recommended as the primary route for cardiac arrest drug administration.5,23–29 There has, however, been a move away from guideline support for the intra-arrest insertion of central venous catheters that featured in some early guidelines, because of the risks associated with their insertion.30

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      This includes producing up-to-date evidence-based European guidelines for the prevention and treatment of cardiac arrest and life threatening emergencies. The first ERC guidelines were presented in Brighton in 1992 and covered basic2 and advanced life support.3 In 1994, Guidelines for Paediatric Life Support (PLS)4 and Guidelines for the Management of Peri-arrest Arrhythmias5 followed at the second Congress in Mainz, with Guidelines for the Basic and Advanced Management of the Airway and Ventilation during Resuscitation at the third Congress in Seville in 1996,6 and updated Guidelines at the 4th Scientific Congress of the ERC in Copenhagen in 1998.7,8

    • 2018 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations Summary

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      There was, however, no difference among patients who received amiodarone, lidocaine, or placebo in the percent of patients with a poor neurological outcome (modified Rankin Scale score 4 or 5) at hospital discharge (5.4% for amiodarone versus 6.1% for lidocaine versus 4.3% for placebo) in the per-protocol population. We did not identify any RCTs published since the 2015 CoSTR [5,6] that evaluated the role of magnesium in the treatment of VF/pVT. The 4 RCTs evaluated in the 2015 CoSTR reported the outcomes of a total of 437 patients [38–41], with the most recent study published in 2002, which noted that the enrolled patients were treated in a manner consistent with the 1992 European resuscitation guidelines [52]. Two of these studies included patients who had arrest rhythms other than VF/pVT [39,40].

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