Glycemia in the post-resuscitation period
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Cited by (58)
Hyperglycemia Alters Expression of Cerebral Metabolic Genes after Cardiac Arrest
2018, Journal of Stroke and Cerebrovascular DiseasesEuropean Resuscitation Council and European Society of Intensive Care Medicine Guidelines for Post-resuscitation Care 2015. Section 5 of the European Resuscitation Council Guidelines for Resuscitation 2015.
2015, ResuscitationCitation Excerpt :Prolonged observation may be necessary after treatment of seizures with sedatives, which will decrease the reliability of a clinical examination.156 There is a strong association between high blood glucose after resuscitation from cardiac arrest and poor neurological outcome.13,15,20,157–163 Although one randomised controlled trial in a cardiac surgical intensive care unit showed that tight control of blood glucose (4.4–6.1 mmol l−1 or 80–110 mg dl−1) using insulin reduced hospital mortality in critically ill adults,164 a second study by the same group in medical ICU patients showed no mortality benefit from tight glucose control.165
European Resuscitation Council Guidelines for Resuscitation 2010 Section 4. Adult advanced life support
2010, ResuscitationCitation Excerpt :In the initial stages of resuscitation there are no clear advantages to using colloid, so use 0.9% sodium chloride or Hartmann's solution. Avoid dextrose, which is redistributed away from the intravascular space rapidly and causes hyperglycaemia, which may worsen neurological outcome after cardiac arrest.498–505 Whether fluids should be infused routinely during cardiac arrest is controversial.
European Resuscitation Council Guidelines for Resuscitation 2010 Section 1. Executive summary
2010, ResuscitationCitation Excerpt :No studies directly address the use of prophylactic anticonvulsant drugs after cardiac arrest in adults. There is a strong association between high blood glucose after resuscitation from cardiac arrest and poor neurological outcome.58,332–338 A large randomised trial of intensive glucose control (4.5–6.0 mmol l−1) versus conventional glucose control (10 mmol l−1 or less) in general ICU patients reported increased 90-day mortality in patients treated with intensive glucose control.339
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Research assistant, National Fund for Scientific Research (Belgium).