Intrapartum fetal pulse oximetry: Fetal oxygen saturation trends during labor and relation to delivery outcome
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Intraoperative management of the neonate
2022, Goldsmith's Assisted Ventilation of the Neonate: An Evidence-Based Approach to Newborn Respiratory Care, Seventh EditionGestational age impacts birth to placental weight ratio and umbilical cord oxygen values with implications for the fetal oxygen margin of safety
2022, Early Human DevelopmentCitation Excerpt :Moreover, retrospective cohort study has shown that infant mortality rates at 39, 40, and 41 weeks` gestation are lower than the overall mortality risk of expectant management for an additional week [22], which is likely to be hypoxia related [20]. Study limitations include the extent to which labor and delivery affect cord O2 findings, with pulse oximetry showing O2 saturation to be marginally decreased through labor [43], although fetal scalp sampling shows PO2 to be little changed until a marginal fall just before delivery with these values then comparable to umbilical artery values [44]. However, cord O2 findings at birth will relate to pre-labor/delivery oxygenation and can be reflective of this if the sample size is sufficient and covariates controlled for with large population-based studies showing cord O2 values to be lower in SGA infants [19,37] as similarly seen with cordocentesis prior to labor [8,10].
Optimizing oxygen therapy for preterm infants at birth: Are we there yet?
2020, Seminars in Fetal and Neonatal MedicineOxygen Therapy in the Delivery Room: What Is the Right Dose?
2018, Clinics in PerinatologyCitation Excerpt :The question remains: if we start at room air, how to best titrate the oxygen to meet these 2 objectives? The fetus in labor has an oxygen saturation of around 50%, which can decrease to as low as 30% without adversely affecting the fetus.11,13,63 Multiple studies have demonstrated that a term newborn takes about 10 minutes after birth to reach an oxygen saturation of greater than 90%.14,15
Maternal body mass index impacts fetal-placental size at birth and umbilical cord oxygen values with implications for regulatory mechanisms
2017, Early Human DevelopmentCitation Excerpt :Study limitations include the categorization of SGAs using birth weights < 10th percentile since some of these infants will be constitutionally small rather than growth restricted, although this classification is widely used for denoting FGR infants. Additionally, labor and delivery are likely to affect fetal oxygenation with pulse oximetry showing oxygen saturation to be marginally decreased through labor [35], although fetal scalp sampling shows PO2 to be little changed until a marginal fall just before delivery with these values then comparable to umbilical artery values [36]. However, umbilical cord PO2 obtained post-delivery must also relate to pre-labor/delivery oxygenation and can be reflective of this if the sample size is sufficient since large population studies show cord oxygen values to be lower with advancing gestation [37] and in FGR infants [16] as similarly seen with cordocentesis prior to labor [38].
Supported by Nellcor, Inc., Hayward, California.