Adenosine versus verapamil in the treatment of supraventricular tachycardia: A randomized double-crossover trial☆
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Cited by (62)
European Resuscitation Council Guidelines 2021: Adult advanced life support
2021, ResuscitationEtripamil: Intranasal Calcium Channel Blocker: A Novel Noninvasive Modality in the Treatment of Paroxysmal Supraventricular Tachycardia
2021, Current Problems in CardiologyCitation Excerpt :Traditional dosing includes a 6-mg IV rapid bolus, injected as proximal or as close to the heart as possible over 1-2 seconds, followed by rapid saline flush. If no response in 1-2 minutes, a second rapid IV bolus of 12 mg may be administered, followed by rapid saline flush.10,11 In addition to coronary vasodilatation, adenosine also can potentially cause bronchoconstriction, which leads to patient reports of shortness of breath, chest tightness, and flushing.
High-dose adenosine for treatment of refractory paroxysmal supraventricular tachycardia
2020, American Journal of Emergency MedicineThyrotoxicosis in a Pediatric Patient with Supraventricular Tachycardia and Borderline Features of Thyroid Storm
2019, AACE Clinical Case ReportsAlternative Treatment Options for Atrioventricular-Nodal-Reentry Tachycardia: An Emergency Medicine Review
2018, Journal of Emergency MedicineCitation Excerpt :If the tachycardia recurs or persists within 1–2 min of adenosine administration, it can be re-administered as a 12-mg dose up to two times. Studies consistently demonstrate approximately 90% termination of SVT within 30 s when two or more doses are used (13–15). However, these studies were completed in the 1990s, and researchers have since questioned whether there are circumstances in which adenosine may not be efficacious at the standard doses.
Part 8: Advanced life support: 2010 International consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations
2010, ResuscitationCitation Excerpt :In adult patients with narrow-complex tachycardia (out-of-hospital and in-hospital), does the use of any drug or combination of drugs, compared with not using drugs (or a standard drug regimen), improve outcomes (e.g., reversion rates)? Five trials supported the use of adenosine in the treatment of narrow-complex tachycardia (LOE 1).272–276 Six trials demonstrated the effectiveness of verapamil in conversion to sinus rhythm (LOE 1).272–275,277,278
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Supported by National Heart Foundation of New Zealand grant 525 and The Hawke's Bay Medical Research Foundation, New Zealand.