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The FORTA (Fit fOR The Aged) List 2018: Third Version of a Validated Clinical Tool for Improved Drug Treatment in Older People

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References

  1. Mc Namara KP, Breken BD, Alzubaidi HAT, et al. Health professional perspectives on the management of multimorbidity and polypharmacy for older patients in Australia. Age Ageing. 2017;46:291–9.

    PubMed  Google Scholar 

  2. Molokhia M, Majeed A. Current and future perspectives on the management of polypharmacy. BMC Fam Pract. 2017;18:70.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Hamilton HJ, Gallagher PF, O’Mahony D. Inappropriate prescribing and adverse drug events in older people. BMC Geriatr. 2009;9:5.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Wauters M, Elseviers M, Vaes B, et al. Too many, too few, or too unsafe? Impact of inappropriate prescribing on mortality, and hospitalization in a cohort of community-dwelling oldest old. Br J Clin Pharmacol. 2016;82:1382–92.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Cadogan CA, Ryan C, Hughes CM. Appropriate polypharmacy and medicine safety: when many is not too many. Drug Saf. 2016;39:109–16.

    Article  PubMed  Google Scholar 

  6. Morley JE. Inappropriate drug prescribing and polypharmacy are major causes of poor outcomes in long-term care. J Am Med Dir Assoc. 2014;15:780–2.

    Article  PubMed  Google Scholar 

  7. Leelakanok N, Holcombe AL, Lund BC, et al. Association between polypharmacy and death: a systematic review and meta-analysis. J Am Pharm Assoc. 2017;57:729–38.

    Article  Google Scholar 

  8. American Geriatrics Society (2012) Beers Criteria Update Expert Panel. American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2012;2012(60):616–31.

    Article  Google Scholar 

  9. Pazan F, Kather J, Wehling M. A systematic review and novel classification of listing tools to improve medication in older people. Eur J Clin Pharmacol. 2019. https://doi.org/10.1007/s00228-019-02634-z.

    Article  PubMed  Google Scholar 

  10. Tommelein E, Mehuys E, Petrovic M, Somers A, Colin P, Boussery K. Potentially inappropriate prescribing in community-dwelling older people across Europe: a systematic literature review. Eur J Clin Pharmacol. 2015;71:1415–27.

    Article  PubMed  Google Scholar 

  11. Kuhn-Thiel AM, Weiss C, Wehling M, The FORTA Authors/Expert Panel Members. Consensus validation of the FORTA (Fit fOR The Aged) list: a clinical tool for increasing the appropriateness of pharmacotherapy in the elderly. Drugs Aging. 2014;31:131–40.

    Article  CAS  PubMed  Google Scholar 

  12. Pazan F, Weiss C, Wehling M, et al. The FORTA (Fit fOR The Aged) List 2015: update of a validated clinical tool for improved pharmacotherapy in the elderly. Drugs Aging. 2016;33:447–9. https://doi.org/10.1007/s40266-016-0371-4.

    Article  PubMed  Google Scholar 

  13. Wehling M. Multimorbidity and polypharmacy: how to reduce the harmful drug load and yet add needed drugs in the elderly? Proposal of a new drug classification: Fit fOR The Aged. J Am Geriatr Soc. 2009;57:560–1.

    Article  PubMed  Google Scholar 

  14. Michalek C, Wehling M, Schlitzer J, Frohnhofen H. Effects of “Fit fOR The Aged” (FORTA) on pharmacotherapy and clinical endpoints—a pilot randomized controlled study. Eur J Clin Pharmacol. 2014;70:1261–7.

    Article  CAS  PubMed  Google Scholar 

  15. Wehling M, Burkhardt H, Kuhn-Thiel AM, Pazan F, Throm C, Weiss C, Frohnhofen H. VALFORTA—a randomized trial to validate the FORTA (“Fit fOR The Aged”) classification. Age Ageing. 2016;45:262–7.

    Article  PubMed  Google Scholar 

  16. Pazan F, Burkhardt H, Frohnhofen H, Weiss C, Throm C, Kuhn-Thiel A, Wehling M. Changes in prescription patterns in older hospitalized patients: the impact of FORTA on disease-related over- and under-treatments. Eur J Clin Pharmacol. 2018;74:339–47.

    Article  PubMed  Google Scholar 

  17. Wehling M. How to use the FORTA (“Fit fOR The Aged”) list to improve pharmacotherapy in the elderly. Drug Res. 2016;66:57–62.

    CAS  Google Scholar 

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Acknowledgements

FORTA List 2018 Initiators and Their Affiliations: Martin Wehling, MD (Creator of the FORTA Concept); Clinical Pharmacology, Center for Geriatric Pharmacology, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Heinrich Burkhardt, MD; 2nd, Medical Department, Center for Geriatrics, University Hospital Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. Stefan Schwarz, MD; Central Institute of Mental Health, Mannheim, Germany. Ulrich Wedding, MD; Division of Palliative Care, University Hospital Jena, Clinic for Internal Medicine II, Erlanger Allee 101, 07740 Jena, Germany.

Expert Panel Members (Raters) and Their Affiliations: Jürgen Bauer, MD; Geriatric Centre of the Medical Faculty of the University of Heidelberg, AGAPLESION Bethanien Hospital Heidelberg, Rohrbacher Straße 149, 69126 Heidelberg, Germany. Heiner K. Berthold, MD; Department of Internal Medicine and Geriatrics, Bielefeld Evangelical Hospital (EvKB), Schildescher Strasse 99, 33611 Bielefeld, Germany. Michael Denkinger, MD; AGAPLESION Bethesda Clinic Ulm, University Hospital Ulm, Zollernring 26, 89073 Ulm, Germany. Peter Dovjak, MD; Gmunden Hospital, Department of Acute Geriatric Medicine, Miller-von-Aichholz-Straße 49, A-4810 Gmunden, Austria. Helmut Frohnhofen, MD; Department of Nephrology, Geriatrics and Internal Medicine, Alfried Krupp Hospital Rüttenscheid, Alfried-Krupp-Straße 21, 45276 Essen, Germany. Markus Gosch, MD; Medical Clinic 2, Geriatric Department, University Hospital of the Paracelsus Medical University, Nürnberg Hospital North, Prof.-Ernst-Nathan-Str. 1, 90419 Nürnberg, Germany. Hans Gutzmann, MD; Hedwigshöhe Hospital, Clinic for Psychiatry, Psychotherapy and Psychosomatic Medicine, Höhensteig 1, 12526 Berlin, Germany. Isabella Heuser-Collier, MD; Charité University Hospital Berlin, Department of Psychiatry and Psychotherapy, University Medicine Berlin, Hindenburgdamm 30, 112203 Berlin, Germany. Friedemann Honecker, MD; General Internal Medicine, Hematology, Senology/Breast medicine, Tumor- und Brustzentrum ZeTuP, Silberturm, Rorschacherstrasse 150, 9006 St. Gallen, Switzerland. Michael Hüll, MD; Clinic for Geriatric Psychiatry and Psychotherapy, Center for Psychiatry Emmendingen, Neubronnstr. 25, 79312 Emmendingen, Germany. Bernhard Iglseder, MD; Department of Geriatric Medicine, Christian-Doppler-Klinik, Paracelsus Medical University, Ignaz-Harrer-Str. 79, 5020 Salzburg, Austria. Ulrich Jaehde, PhD; Friedrich-Wilhelms-University Bonn, Pharmaceutical Institute, Clinical Pharmacy, An der Immenburg 4, 53121 Bonn, Germany. Siegfried Kasper, MD; Department of Psychiatry and Psychotherapy, Medical University of Vienna, AKH, Währinger Gürtel 18-20, A-1090 Vienna, Austria. Gerald Kolb, MD; Department of Geriatric Medicine, Bonifatius Hospital Lingen gGmbH, Wilhelmstraße 13, 49808 Lingen (Ems), Germany. Reto W. Kressig, MD; University Basel, Memory Clinic – Academic Geriatric Medicine, Burgfelderstrasse 101, 4055 Basel, Switzerland. Anja Kwetkat, MD; Jena University Hospital, Department of Geriatric Medicine, Bachstraße 18, 07740 Jena, Germany. Thomas Münzer, MD, EAMA Board Member; Competence Center Healthy Ageing, Geriatric Clinic St. Gallen AG, Rorschacherstrasse 94, 9000 St. Gallen, Switzerland. Christoph Schindler, MD; Clinical Research Center Hannover, CRC- MHH Core Facility, Feodor-Lynen-Strasse 15, 30625 Hannover, Germany. Matthias Schuler, MD; Diakonissenhospital Mannheim, Geriatric Clinic, Speyerer Straße 91-93, 68163 Mannheim, Germany. Ralf-Joachim Schulz, MD; Geriatric Clinic at the St.-Marien Hospital, Kunibertkloster 11-13 50668 Köln, Germany. Ulrike Sommeregger, MD; Hietzing Hospital and Neurological Center Rosenhügel, Wolkersbergenstraße 1, 1130 Vienna, Department of Acute Geriatric Medicine, Donauspital, Langobardenstraße 122, 120 Vienna, Austria. Andrej Zeyfang, MD; Clinic for General Internal, Geriatric and Palliative Medicine, KLINIK OSTFILDERN-RUIT, Academic Educational hospital of the University Tübingen, Hedelfinger Str. 166, 73760 Ostfildern, Germany.

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Correspondence to Martin Wehling.

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Martin Wehling was employed by AstraZeneca R&D, Mölndal, as the director of discovery medicine (translational medicine) from 2003 to 2006, while on sabbatical leave from his professorship at the University of Heidelberg. Since returning to this position in January 2007, he has received lecturing and consulting fees from Sanofi-Aventis, Bayer, Berlin-Chemie, Boehringer-Ingelheim, Aspen, Novartis, Takeda, Roche, Pfizer, Bristol-Myers, Daichii-Sankyo, Lilly, Otsuka, Novo-Nordisk, Shire, and LEO Pharma. Farhad Pazan and Christel Weiss have no conflicts of interest that are directly relevant to the contents of this letter.

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FORTA members are listed in the Acknowledgements section.

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Pazan, F., Weiss, C., Wehling, M. et al. The FORTA (Fit fOR The Aged) List 2018: Third Version of a Validated Clinical Tool for Improved Drug Treatment in Older People. Drugs Aging 36, 481–484 (2019). https://doi.org/10.1007/s40266-019-00669-6

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