Abstract
The intentional consumption and use of stimulants, such as caffeine, are known to have numerous interactions with the human cardiovascular system. Ex vivo studies have shown caffeine-induced vasoconstriction of coronary arteries (Forman et al. in Ann Emerg Med 29:178–180, 1997). We report on a case of a 17-year-old male who presented with angina and an abnormal electrocardiogram (ECG) concerning for ST elevation myocardial infarct. He was found to have diffuse ECG changes and markedly elevated cardiac enzymes. A transthoracic echocardiogram revealed a reduced left ventricular (LV) systolic function as well as segmental wall motion abnormalities consistent with an ischemic insult. The patient admitted to consuming near lethal doses of caffeine immediately preceding his angina. He was diagnosed with coronary vasospasms as a result of stimulant use. During hospitalization, ECG changes resolved, cardiac enzymes started trending downward, and LV systolic function returned to normal, all consistent with stunned myocardium that fully recovered. This case strongly suggests that overuse of stimulants, such as caffeine, should be considered in patients presenting with coronary vasospasms, particularly in teenagers and young adults.
References
Forman, J., Aizer, A., & Young, C. R. (1997). Myocardial infarction resulting from caffeine overdose in an anorectic woman. Annals of Emergency Medicine, 29, 178–180.
Owens, B. (2010). Authorities say Four Loko equals a six-pack of beer and five coffees. DailyRecordNews.com. October 27, 2010.
Echeverri, D., et al. (2010) Caffeine’s vascular mechanisms of action. International Journal of Vascular Medicine, 2010. Article ID 834060.
Berger, A. J., & Alford, K. (2009). Cardiac arrest in a young man following excess consumption of caffeinated “energy drinks”. The Medical Journal of Australia, 190(1), 41–43.
Holmgren, P., Norden-Pettersson, L., & Ahlner, J. (2004). Caffeine fatalities–four case reports. Forensic Science International, 139, 71–73.
Cooper, L. T., McKenna, W. J., & Yeon, S. B. (2011) Clinical manifestations and diagnosis of myocarditis in adults. UpToDate. Last literature review version 19.3: September 2011.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Wilson, R.E., Kado, H.S., Samson, R. et al. A Case of Caffeine-Induced Coronary Artery Vasospasm of a 17-Year-Old Male. Cardiovasc Toxicol 12, 175–179 (2012). https://doi.org/10.1007/s12012-011-9152-9
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12012-011-9152-9