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The influence of resilience on fatigue in cancer patients undergoing radiation therapy (RT)

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Abstract

Purpose

The primary goal of the study was to determine if resilience influences fatigue in a consecutive sample of cancer patients treated with radiotherapy (RT) at the beginning and at the end of the treatment.

Methods

Out of an initial sample of 250 patients, 239 could be assessed at the beginning of their RT. Two hundred and eight patients were reassessed at the end of RT 4–8 weeks later. Measures comprised the Resilience Scale (RS), the Multidimensional Fatigue Inventory (MFI), and the SF-12 as a measure of health related Quality of Life (QoL). Medical data were continuously registered.

Results

As hypothesized, the sample revealed higher scores in the MFI and lower scores in the SF-12 than normative samples. Resilience scores were higher than in the norm population. Fatigue increased during RT. Using multiple regression analyses, fatigue scores at the beginning of treatment were shown to be higher in inpatients and patients undergoing palliative treatment. Initial fatigue was best predicted by the patients’ initial resilience scores. Changes of fatigue scores during RT depended on initial scores, decrease in Hb and the patients’ experience with RT. Resilience could not be determined as a predictor of changes in fatigue during RT.

Conclusions

The study confirmed that fatigue is an important problem among RT patients. Resilience turned out to powerfully predict the patients’ fatigue at least early in RT. This result is in line with other studies, showing resilience to be an important psychological predictor of QoL and coping in cancer patients. On the other hand, resilience seems to have little influence on treatment related fatigue during RT.

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Authors and Affiliations

  1. Institute of Psychosocial Medicine and Psychotherapy, University Hospital, Friedrich-Schiller University Jena, Stoystr. 3, Jena, 07740, Germany

    Bernhard Strauss, Christina Brix, Sebastian Fischer, Karena Leppert, Bernd Roehrig & Christine Schleussner

  2. Department of Radiation Oncology, University Hospital, Friedrich Schiller University, Jena, Germany

    Jürgen Füller & Thomas G. Wendt

Authors
  1. Bernhard Strauss
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  2. Christina Brix
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  3. Sebastian Fischer
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  4. Karena Leppert
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  5. Jürgen Füller
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  6. Bernd Roehrig
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  7. Christine Schleussner
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  8. Thomas G. Wendt
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Corresponding author

Correspondence to Bernhard Strauss.

Additional information

This work was supported by the Wilhelm-Sander-Foundation (FKZ 2002.071.1).

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Strauss, B., Brix, C., Fischer, S. et al. The influence of resilience on fatigue in cancer patients undergoing radiation therapy (RT). J Cancer Res Clin Oncol 133, 511–518 (2007). https://doi.org/10.1007/s00432-007-0195-z

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  • DOI: https://doi.org/10.1007/s00432-007-0195-z

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