Abstract
Objective
The objective of the study is to characterize the maternal and neonatal morbidities of women with placenta previa.
Study design
This retrospective group study used the Consortium on Safe Labor electronic database, including 12 clinical centers, and 19 hospitals. Patients with placenta previa noted at the time of delivery were included. Maternal and neonatal variables were compared to a control group of women undergoing cesarean delivery with no previa. Logistic regression and general linear regression were used for the analysis, with p < 0.05 significance.
Results
There were 19,069 patients in the study: 452 in the placenta previa group and 18,617 in the control group. Neonates born to mothers with placenta previa had lower gestational ages and birth weights. In univariate analysis only, these neonates were at increased risk of lower 5 min Apgar scores, neonatal intensive care unit admission, anemia, respiratory distress syndrome, mechanical ventilation, and intraventricular hemorrhage. There was no association of placenta previa with small for gestational age infants, congenital anomalies or death. As previously shown, women with placenta previa have significantly more maternal morbidities.
Conclusion
Increased maternal morbidity was noted; however, only those neonatal morbidities associated with preterm delivery occurred in the placenta previa group.
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Acknowledgments
The data included in this paper were obtained from the Consortium on Safe Labor, which was supported by the Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, through Contract No. HHSN267200603425C. Institutions involved in the Consortium include, in alphabetical order: Baystate Medical Center, Springfield, MA, USA; Cedars-Sinai Medical Center Burnes Allen Research Center, Los Angeles, CA, USA; Christiana Care Health System, Newark, DE, USA; Georgetown University Hospital, MedStar Health, Washington, DC, USA; Indiana University Clarian Health, Indianapolis, IN, USA; Intermountain Healthcare and the University of Utah, Salt Lake City, UT, USA; Maimonides Medical Center, Brooklyn, NY, USA; MetroHealth Medical Center, Cleveland, OH, USA; Summa Health System, Akron City Hospital, Akron, OH, USA; The EMMES Corporation, Rockville MD, USA (Data Coordinating Center); University of Illinois at Chicago, Chicago, IL, USA; University of Miami, Miami, FL, USA; and University of Texas Health Science Center at Houston, Houston, TX, USA. The named authors alone are responsible for the views expressed in this manuscript, which does not necessarily represent the decisions or the stated policy of the NICHD. Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, through a contract (Contract No. HHSN267200603425C). University of Illinois at Chicago (UIC) Center for Clinical and Translational Science (CCTS), Award Number UL1RR029879 from the National Center for Research Resources.
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Lal, A.K., Hibbard, J.U. Placenta previa: an outcome-based cohort study in a contemporary obstetric population. Arch Gynecol Obstet 292, 299–305 (2015). https://doi.org/10.1007/s00404-015-3628-y
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DOI: https://doi.org/10.1007/s00404-015-3628-y