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Glukokortikoide

Glucocorticoids

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Literatur

  1. Hench PS, Kendall EC, Slocumb CH et al (1949) The effect of a hormone of the adrenal cortex (17-hydroxy-11-dehydrocorticosterone: Compound E) and of pituitary adrenocorticotropic hormone on rheumatoid arthritis. Preliminary report. Proc Staff Meet Mayo Clin 24:181–197

    CAS  PubMed  Google Scholar 

  2. Hench PS, Kendall EC, Slocumb CH, Polley HF (1949) Adrenocortical hormone in arthritis : preliminary report. Ann Rheum Dis 8:97–104

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Hench PS (1950) The present status of cortisone and ACTH. Proc R Soc Med 43:769–773

    CAS  PubMed  PubMed Central  Google Scholar 

  4. Benedek TG (2011) History of the development of corticosteroid therapy. Clin Exp Rheumatol 29(suppl.68):5–12

    Google Scholar 

  5. Hollander JL, Brown EM, Jessar RA et al (1951) Hydrocortisone and cortisone injected into arthritic joints. JAMA 147:1629–1635

    Article  CAS  Google Scholar 

  6. Freyberg RH, Traeger CH, Patterson M et al (1951) Problems of prolonged cortisone treatment for rheumatoid arthritis. JAMA 147:1538–1543

    Article  CAS  Google Scholar 

  7. De Andrade JR, McCormick JN, Hill AGS (1964) Small doses of prednisolone in the management of rheumatoid arthritis. Ann Rheum Dis 23:158–162

    Article  PubMed Central  Google Scholar 

  8. Polley HF, Slocumb CH, Ward LE, Hench PS (1955) Recognition and treatment of patients with chronic hypercortisonism. Ann Rheum Dis 14:416–417

    Google Scholar 

  9. Pincus T, Cutolo M (2015) Clinical trials documenting the efficacy of low-dose-glucocorticoids in rheumatoid arthritis. Neuroimmunomodulation 22:46–50

    Article  CAS  PubMed  Google Scholar 

  10. Harris ED Jr, Emkey RD, Nichols JE, Newberg A (1983) Low dose prednisone therapy in rheumatoid arthritis: a double blind study. J Rheumatol 10:713–721

    PubMed  Google Scholar 

  11. Kirwan JR (1995) The effects of glucocorticoids on joint destruction in rheumatoid arthritis. N Engl J Med 333:142–146

    Article  CAS  PubMed  Google Scholar 

  12. Boers M, Verhoeven AC, Markusse HM et al (1997) Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis. Lancet 350:309–318

    Article  CAS  PubMed  Google Scholar 

  13. Everdingen AA van, Jacobs JWG, Reesema DRS van, Bijlsma JWJ (2002) Low-dose prednisone therapy for patients with early active rheumatoid arthritis: clinical efficacy, disease-modifying properties, and side effects. Ann Intern Med 136:1–12

    Article  PubMed  Google Scholar 

  14. Svensson B, Boonen A, Albertsson K et al (2005) Low-dose prednisolone in addition to the initial disease-modifying antirheumatic drug in patients with early active rheumatoid arthritis reduces joint destruction and increases the remission rate: a two-year randomized trial. Arthritis Rheum 52:3360–3370

    Article  CAS  PubMed  Google Scholar 

  15. Wassenberg S, Rau R, Steinfeld P, Zeidler H (2005) Very low-dose prednisolone in early rheumatoid arthritis retards radiographic progression over two years: a multicenter, double-blind, placebo-controlled trial. Arthritis Rheum 52:3371–3380

    Article  CAS  PubMed  Google Scholar 

  16. Buttgereit F, Doering G, Schaeffler A et al (2008) Efficacy of modified-release versus standard prednisone to reduce duration of morning stiffness of the joints in rheumatoid arthritis (CAPRA-1): a double-blind, randomised controlled trial. Lancet 371:205–214

    Article  CAS  PubMed  Google Scholar 

  17. Bakker MF, Jacobs JW, Welsing PM et al (2012) Low-dose prednisone inclusion in a methotrexate-based, tight control strategy for early rheumatoid arthritis: a randomized trial. Ann Intern Med 156:329–339

    Article  PubMed  Google Scholar 

  18. Montecucco C, Todoerti M, Sakellariou G et al (2012) Low-dose oral prednisone improves clinical and ultrasonographic remission rates in early rheumatoid arthritis: results of a 12-month open-label randomised study. Arthritis Res Ther 14:R112

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Buttgereit F, Mehta D, Kirwan J et al (2013) Low-dose prednisone chronotherapy for rheumatoid arthritis: a randomised clinical trial (CAPRA-2). Ann Rheum Dis 72:204–210

    Article  CAS  PubMed  Google Scholar 

  20. Felson DT, Anderson JJ, Boers M et al (1995) American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis. Arthritis Rheum 38:727–735

    Article  CAS  PubMed  Google Scholar 

  21. Goes MC van der, Jacobs JW, Jurgens MS et al (2013) Are changes in bone mineral density different between groups of early rheumatoid arthritis patients treated according to a tight control strategy with or without prednisone if osteoporosis prophylaxis is applied? Osteoporos Int 24:1429–1436

    Article  CAS  PubMed  Google Scholar 

  22. Weber G, Keitel W (1973) Die Kortisonoidbehandlung der rheumatoiden Arthritis. Mitteilungsbl Inst Rheum Dresd 11:8

    Google Scholar 

  23. Weber G, Keitel W (1975) Ergebnisse der Kortisonoid-Dosisreduktion bei Rheumatoider Arthritis. Dtsch Gesundheitsw 30:924–927

    Google Scholar 

  24. Huscher D, Deutsches Rheumaforschungszentrum, persönliche Mitteilung, 2.3.2016

  25. Albrecht K, Callhoff J, Schneider M, Zink A (2015) High variability in glucocorticoid starting doses in patients with rheumatoid arthritis: observational data from an early arthritis cohort. Rheumatol Int 35:1377–1384

    Article  CAS  PubMed  Google Scholar 

  26. Ter Wee MM, Uyl D den, Boers M et al (2015) Intensive combination treatment regimens, including prednisolone, are effective in treating patients with early rheumatoid arthritis regardless of additional etanercept: 1‑year results of the COBRA-light open-label, randomised, non-inferiority trial. Ann Rheum Dis 74:1233–1240

    Article  PubMed  Google Scholar 

  27. Smolen JS, Landewé R, Breedveld FC et al (2014) EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update. Ann Rheum Dis 73:492–509

    Article  CAS  PubMed  Google Scholar 

  28. Smolen JS, Landewé R, Breedveld FC et al (2010) EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs. Ann Rheum Dis 69:964–975

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  29. Gaujoux-Viala C, Nam JL, Ramiro S et al (2014) Efficacy of conventional synthetic disease-modifying antirheumatic drugs, glucocorticoids and tofacitinib—a systematic literature review informing the 2013 update of the EULAR recommendations for management of rheumatoid arthritis. Ann Rheum Dis 73:510–515

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  30. Strehl C, Bijlsma JWJ, Wit M de et al (2016) Defining conditions where long-term glucocorticoid treatment has an acceptably low level of harm in chronic inflammatory rheumatic diseases: A point of view from an EULAR task force. Ann Rheum Dis. doi:10.1136/annrheumdis-2015-208916

  31. Ramamoorthy S, Cidlowski JA (2016) Corticosteroids: mechanisms of action in health and disease. Rheum Dis Clin North Am 42:15–31

    Article  PubMed  Google Scholar 

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Correspondence to E. Gromnica-Ihle.

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E. Gromnica-Ihle gibt an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine vom Autor durchgeführten Studien an Menschen oder Tieren.

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U. Müller-Ladner, Bad Nauheim

H.-M. Lorenz, Heidelberg

M. Schneider, Düsseldorf

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Gromnica-Ihle, E. Glukokortikoide. Z Rheumatol 75, 591–594 (2016). https://doi.org/10.1007/s00393-016-0115-1

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