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Maßnahmen zur Optimierung von Medikamentenverordnungen für ältere Menschen in Pflegeeinrichtungen

Interventions to optimise prescribing for older people in care homes

  • Cochrane Corner Geriatrie
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Literatur

  1. Alldred DP, Raynor DK, Hughes C, Barber N, Chen TF, Spoor P (2013) Interventions to optimise prescribing for older people in carehomes. Cochrane Database of Systematic Reviews, Issue 2. https://doi.org/10.1002/14651858.CD009095.pub2

    Article  PubMed  Google Scholar 

  2. Nyborg G, Brekke M, Straand J, Gjelstad S, Romoren M (2017) Potentially inappropriate medication use in nursing homes: an observational study using the NORGEP-NH criteria. BMC Geriatr 17(1):220

    Article  Google Scholar 

  3. Endres HG, Kaufmann-Kolle P, Steeb V, Bauer E, Bottner C, Thurmann P (2016) Association between potentially inappropriate medication (PIM) use and risk of hospitalization in older adults: an observational study based on routine data comparing PIM use with use of PIM alternatives. PLoS ONE 11(2):e146811

    Article  Google Scholar 

  4. Richter T, Mann E, Meyer G, Haastert B, Kopke S (2012) Prevalence of psychotropic medication use among German and Austrian nursing home residents: a comparison of 3 cohorts. J Am Med Dir Assoc 13(2):187.e7–187.e13

    Article  Google Scholar 

  5. Davies EA, O’Mahony MS (2015) Adverse drug reactions in special populations—the elderly. Br J Clin Pharmacol 80(4):796–807

    Article  CAS  Google Scholar 

  6. Hoffmann F, Boeschen D, Dorks M, Herget-Rosenthal S, Petersen J, Schmiemann G (2016) Renal insufficiency and medication in nursing home residents. A cross-sectional study (IMREN). Dtsch Ärztebl Int 113(6):92–98

    PubMed  PubMed Central  Google Scholar 

  7. Bakken MS, Schjott J, Engeland A, Engesaeter LB, Ruths S (2016) Antipsychotic drugs and risk of hip fracture in people aged 60 and older in Norway. J Am Geriatr Soc 64(6):1203–1209

    Article  Google Scholar 

  8. Cioltan H, Alshehri S, Howe C, Lee J, Fain M, Eng H et al (2017) Variation in use of antipsychotic medications in nursing homes in the United States: a systematic review. BMC Geriatr 17(1):32

    Article  Google Scholar 

  9. Liperoti R, Sqanqa F, Landi F, Topinkova E, Denkinger MD, van der Roest HG et al (2017) Antipsychotic drug interactions and mortality among nursing home residents with cognitive impairment. J Clin Psychiatry 78:e76–e82

    Article  Google Scholar 

  10. Houghton J, Kirthisinga V, Desborough JA (2014) Multi-professional medication reviews in care homes for older people: results from the CARE MED randomized controlled trial. Age Ageing 43:ii19–ii20

    Article  Google Scholar 

  11. Desborough J, Houghton J, Wood J, Wright D, Holland R, Sach T, Ashwell S, Shaw V (2011) Multi-professional clinical medication reviews in care homes for the elderly: study protocol for a randomised controlled trial with cost effectiveness analysis. Trials 12:218

    Article  Google Scholar 

  12. Kovach CR, Hekel B, Rababa M (2015) Feasibility testing of a protocol to stop ineffective drug and nondrug treatments. West J Nurs Res 37(11):1404–1422

    Article  Google Scholar 

  13. Potter K, Flicker L, Page A, Etherton-Beer C (2016) Deprescribing in frail older people: a randomised controlled trial. PLoS ONE 11(3):e149984. https://doi.org/10.1371/journal.pone.0149984 (eCollection 2016)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Wouters H, Scheper J, Koning H, Brouwer C, Twisk JW, van der Meer H, Boersma F, Zuidema SU, Taxis K (2017) Discontinuing inappropriate medication use in nursing home residents: a cluster randomized controlled trial. Ann Intern Med 167(9):609–617

    Article  Google Scholar 

  15. Anrys P, Strauven G, Boland B et al (2016) Collaborative approach to Optimise MEdication use for Older people in Nursing homes (COME-ON): study protocol of a cluster controlled trial. Implement Sci 11:35

    Article  Google Scholar 

  16. Strauven G, Anrys P, Vandael E, Henrard S, De Lepeleire J, Spinewine A, Foulon V (2019) Cluster-controlled trial of an intervention to improve prescribing in nursing homes study. J Am Med Dir Assoc 20(11):1404–1411

    Article  Google Scholar 

  17. Husebø BS, Ballard C, Aarsland D, Selbaek G, Slettebo DD, Gulla C, Aasmul I, Habiger T, Elvegaard T, Testad I, Flo E (2019) The effect of a multicomponent intervention on quality of life in residents of nursing homes: a randomized controlled trial (COSMOS). J Am Med Dir Assoc 20(3):330–339

    Article  Google Scholar 

  18. Gulla C, Flo E, Kjome RLS, Husebo BS (2019) Implementing a novel strategy for interprofessional medication review using collegial mentoring and systematic clinical evaluation in nursing homes (COSMOS). BMC Geriatr 19(1):130

    Article  Google Scholar 

  19. Millar AN, Daffu-O’Reilly A, Hughes CM et al (2017) Development of a core outcome set for effectiveness trials aimed at optimising prescribing in older adults in care homes. Trials 18(1):175

    Article  Google Scholar 

  20. Beuscart JB, Knol W, Cullinan S et al (2018) International core outcome set for clinical trials of medication review in multi-morbid older patients with polypharmacy. BMC Med 16:21

    Article  Google Scholar 

  21. Cameron ID, Dyer SM, Panagoda CE, Murray GR, Hill KD, Cumming RG, Kerse N (2018) Interventions for preventing falls in older people in care facilities and hospitals. Cochrane Database Syst Rev 9:CD5465

    PubMed  Google Scholar 

  22. Richter T, Meyer G, Möhler R, Köpke S (2012) Psychosocial interventions for reducing antipsychotic medication in care home residents. Cochrane Database Syst Rev 12:CD8634

    PubMed  Google Scholar 

  23. Crocker T, Forster A, Young J, Brown L, Ozer S, Smith J, Green J, Hardy J, Burns E, Glidewell E, Greenwood DC (2013) Physical rehabilitation for older people in long-term care. Cochrane Database Syst Rev 2:CD4294

    Google Scholar 

  24. Watt JA, Goodarzi Z, Veroniki AA et al (2019) Comparative efficacy of interventions for aggressive and agitated behaviors in dementia. Ann Intern Med 171(9):633–642

    Article  Google Scholar 

  25. Ho JM, Tung J, Maitland J, Mangin D, Thabane L, Pavlin JM, Alfonsi J, Holbrook A, Straus S, Benjamin S (2018) GeriMedRisk, a telemedicine geriatric pharmacology consultation service to address adverse drug events in long-term care: a stepped-wedge cluster randomized feasibility trial protocol (ISRCTN17219647). Pilot Feasibility Stud 4:116

    Article  Google Scholar 

  26. Krause O, Wiese B, Doyle IM, Kirsch C, Thürmann P, Wilm S, Sparenberg L, Stolz R, Freytag A, Bleidorn J, Junius-Walker U (2019) Multidisciplinary intervention to improve medication safety in nursing home residents: protocol of a cluster randomised controlled trial (HIOPP-3-iTBX study). BMC Geriatr 19(1):24

    Article  Google Scholar 

  27. Kua CH, Yeo CYY, Char CWT, Tan CWY, Tan PC, Mak VS, Lee SWH, Leong IY (2017) Nursing home team-care deprescribing study: a stepped-wedge randomised controlled trial protocol. BMJ Open 7(5):e15293

    Article  Google Scholar 

  28. Mestres Gonzalvo C, de Wit HA, van Oijen BP, Hurkens KP, Janknegt R, Schols JM, Mulder WJ, Verhey FR, Winkens B, van der Kuy PM (2017) Supporting clinical rules engine in the adjustment of medication (SCREAM): protocol of a multicentre, prospective, randomised study. BMC Geriatr 17(1):35

    Article  Google Scholar 

  29. Pouw CAM, Smalbrugge M, van Marum RJ, Hugtenburg JG, Hertogh CMPM (2018) Improving medication prescription in the context of advanced care planning for patients receiving nursing home care (IMPETUS): study protocol of a cluster randomized controlled trial. Int J Clin Pharm 40(2):489–489

    Google Scholar 

  30. Sluggett JK, Chen EYH, Ilomäki J, Corlis M, Hilmer SN, Van Emden J, Ooi CE, Nguyen KH, Comans T, Hogan M, Caporale T, Edwards S, Quirke L, Patching A, Bell JS (2018) SImplification of Medications Prescribed to Long-tErm care Residents (SIMPLER): study protocol for a cluster randomised controlled trial. Trials 19(1):37

    Article  Google Scholar 

  31. U.S. National Library of Medicine (2016) Enhancing the detection and management of adverse drug events in nursing homes. https://clinicaltrials.gov/show/nct01531088. Zugegriffen: 3. Dezember 2019

  32. U.S. National Library of Medicine (2014) Pharmaceutical care in VA nursing home. https://clinicaltrials.gov/show/nct01823757. Zugegriffen: 3. Dezember 2019

  33. U.S. National Library of Medicine (2019) Deprescribing in a long term care facility. https://clinicaltrials.gov/show/nct03091153. Zugegriffen: 3. Dezember 2019

  34. U.S. National Library of Medicine (2018) Impact of a hospital medication expertise on unplanned hospitalizations at 3 months of nursing homes patients (TEM-EHPAD). https://clinicaltrials.gov/show/NCT03640845. Zugegriffen: 3. Dezember 2019

  35. U.S. National Library of Medicine (2019) Randomised, controlled trial of an individual deprescribing intervention for nursing homes residents (OLD-NH-IdeI). https://clinicaltrials.gov/show/NCT03655405. Zugegriffen: 3. Dezember 2019

  36. U.S. National Library of Medicine (2018) Opportunities and limits to deprescribing in nursing homes:quality circle deprescribing module (OLD-NH-QC-deMo). https://clinicaltrials.gov/show/NCT03688542. Zugegriffen: 3. Dezember 2019

  37. U.S. National Library of Medicine (2019) Psychotropic drug use in the elderly living in nursing homes and the influence of a structured drug review. https://clinicaltrials.gov/show/NCT03736577. Zugegriffen: 3. Dezember 2019

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Authors and Affiliations

  1. Zentrum für Geriatrie und Gerontologie Freiburg, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Freiburg, Deutschland

    Sebastian Voigt-Radloff

  2. Institut für Evidenz in der Medizin (für Cochrane Deutschland Stiftung), Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Freiburg, Deutschland

    Sebastian Voigt-Radloff, Claudia Bollig & Gabriel Torbahn

  3. AGAPLESION Bethesda Ulm, Geriatrisches Zentrum Ulm/Alb-Donau, Geriatrische Forschung der Universität Ulm, Ulm, Deutschland

    Michael Denkinger

  4. Geriatrisches Zentrum, Universität Heidelberg, Heidelberg, Deutschland

    Jürgen Bauer

Authors
  1. Sebastian Voigt-Radloff
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  2. Claudia Bollig
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  3. Gabriel Torbahn
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  4. Michael Denkinger
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  5. Jürgen Bauer
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Corresponding author

Correspondence to Sebastian Voigt-Radloff.

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Interessenkonflikt

J. Bauer: wissenschaftliche Förderung: Nestlé, Nutricia Danone; Beratungstätigkeit: Nestlé, Nutricia Danone; Vortragshonorare: Nestlé, Nutricia Danone, Fresenius, Bayer, Novartis, Pfizer. Sämtliche Einnahmen aus obigen Tätigkeiten gehen an seine Institution. S. Voigt-Radloff, C. Bollig, G. Torbahn und M. Denkinger geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

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Voigt-Radloff, S., Bollig, C., Torbahn, G. et al. Maßnahmen zur Optimierung von Medikamentenverordnungen für ältere Menschen in Pflegeeinrichtungen. Z Gerontol Geriat 53, 37–43 (2020). https://doi.org/10.1007/s00391-019-01673-6

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