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Acute kidney injury in elderly intensive care patients: a review

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Abstract

The elderly are at high risk for acute kidney injury (AKI). With the aging of the population, the demand for intensive care unit (ICU) admission from older patients will continue to rise, and this clinical entity will likely become increasingly common. In this article we review the relevant literature, discuss the age-related changes that render older people prone to AKI development, and examine the most frequent etiologies for renal impairment in these patients. We also consider the difficulties in achieving an early diagnosis in the elderly ICU patient, the particularities related to AKI treatment in this age group, and the data available on differences in renal recovery and mortality between the young and the old with renal injury. More importantly, we highlight the methods for prevention of AKI development or worsening in the elderly critically ill patient.

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Authors and Affiliations

  1. Department of Nephrology, San Bortolo Hospital, Viale Rodolfi 37, 36100, Vicenza, Italy

    Alexandra Chronopoulos, Dinna N. Cruz & Claudio Ronco

  2. Department of Medicine, Hôpital Hôtel-Dieu de Lévis, 143, rue Wolfe, Lévis, QC, G6V 3Z1, Canada

    Alexandra Chronopoulos

  3. Division of Nephrology, University of Virginia Health System, P.O. Box 800133, Charlottesville, VA, 22908, USA

    Mitchell H. Rosner

  4. International Renal Research Institute Vicenza (IRRIV), Vicenza, Italy

    Dinna N. Cruz & Claudio Ronco

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  1. Alexandra Chronopoulos
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  4. Claudio Ronco
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Correspondence to Claudio Ronco.

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Chronopoulos, A., Rosner, M.H., Cruz, D.N. et al. Acute kidney injury in elderly intensive care patients: a review. Intensive Care Med 36, 1454–1464 (2010). https://doi.org/10.1007/s00134-010-1957-7

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