Zusammenfassung
Hintergrund
Die zunehmende Lebenserwartung schafft viele Alte nach Überstehen des kritischen Alters für Herz- und Gefäßerkrankungen ihren Tumor und später die Demenz erleben.
Fragestellung
Unter den Tumoren des Mannes dominiert das Prostatakarzinom (PCa), dessen Inzidenz und Prävalenz durch die Ausweitung der Früherkennung in den letzten Jahren PSA-getriggert (prostataspezifisches Antigen) fortlaufend zugenommen haben. Werden klinische Relevanz und Lebensqualität der Betroffenen kritisch eingeschätzt, führt das zu der Forderung, die Früherkennung wie auch die Indikation zur einer Therapie an die Lebenserwartung und an die PSA-Werte zu adaptieren. So können Überdiagnosen und Übertherapie vermieden werden. Während hier Einsicht hilft, gilt es für 2030 ca. 1,8 Mio. Demenzkranke hinzunehmen.
Schlussfolgerung
In unserem Gesundheitswesen wird es zu einer Geriatrisierung kommen, die eine größere Zahl Geriatrischer Abteilungen an den Kliniken und Kooperationsmodelle zwischen Geriatrie und anderen Fachabteilungen schaffen wird. Die Ausbildungsinhalte der Studenten und Altersaspekte in der Fort- und Weiterbildung müssen einen qualifizierten Nachwuchs entstehen lassen. Nur so kann die durch den demografischen Wandel bedingte Herausforderung in dem Fach Geriatrie angenommen und bewältigt werden, indem bei Ärzten und Pflegenden für Nachwuchs gesorgt wird.
Abstract
Background
Increasing life expectancy means growing numbers of elderly survive the critical age for cardiac and vascular diseases only to later experience cancer and dementia.
Objectives
Of the types of cancer affecting men, prostate cancer continues to be diagnosed early by prostate-specific antigen (PSA) screening. The clinical relevance and quality of life of those affected must be critically judged. Depending on life expectancy, active surveillance (AS) and watchful waiting (WW) will be increasingly used in geriatric patients. Risk stratification as guided by CGA facilitates the therapeutic decisions of urologists and spares metastatic castration-resistant prostate cancer patients from unnecessary and adverse overtreatment. By 2030, approximately 1.8 million people will have dementia.
Conclusions
Thus, in the future, the health care system will have to treat an aging population, which will require the creation of increasing numbers of geriatric hospital departments and cooperative models between geriatrics and other specialties. The future training of medical students and continuing medical education must also be further developed to include aspects on aging. Only in this manner will it be possible to effectively confront the challenges associated with demographic change in the specialty of geriatrics.
Literatur
Aguirreche E, Zeppenfeld G, Kolb GF (2003) „Memory-clinics“ in German-speaking countries. Z Gerontol Geriatr 36:183–188
Balducci L, Extermann M (2000) Management of cancer in the older person: a practical approach. Oncologist 5:224–237
Beermann S, Chakkalakal D, Muckelbauer R et al (2014) „We talk it over“–mixed-method study of interdisciplinary collaborations in private practice among urologists and oncologists in Germany. BMC Cancer 14:746
Beermann S, Weissbach L (2012) Interdisciplinary treatment of urological tumors: a mixed-method study. Urologe A 51:1085–1088
Cerny T, Gallen KS (2011) Jahrestagung der DGHO, OeGHO, SGMO und SGH. Basel
O Neil D, Hastie I, Williams B (2004) Developing specialist healthcare for older people: a challenge for the European Union. J Nutr Health Aging 8:109–112
Dall’Era MA, Albertsen PC, Bangma C et al (2012) Active surveillance for prostate cancer: a systematic review of the literature. Eur Urol 62:976–983
Droz JP, Aapro M, Balducci L et al (2014) Management of prostate cancer in older patients: updated recommendations of a working group of the International Society of Geriatric Oncology. Lancet Oncol 15:404–414
Droz JP, Balducci L, Bolla M et al (2010) Management of prostate cancer in older men: recommendations of a working group of the International Society of Geriatric Oncology. BJU Int 106:462–469
Ekdahl A, Fiorini A, Maggi S et al (2012) Geriatric Care in Europe – the EUGMS Survey Part II: Malta, Sweden and Austria. Eur Geriatr Med (EGM) 3:388–391
Elshaug AG, Watt AM, Mundy L, Willis CD (2012) Over 150 potentially low-value health care practices: an Australian study. Med J Aust 197:556–560
Extermann M, Aapro M, Bernabei R et al (2005) Use of comprehensive geriatric assessment in older cancer patients: recommendations from the task force on CGA of the International Society of Geriatric Oncology (SIOG). Crit Rev Oncol Hematol 55:241–252
Extermann M, Boler I, Reich RR et al (2011) Predicting the risk of chemotherapy toxicity in older patients: the Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score. Cancer 118:3377–3386
Kolb G, Andersen-Ranberg K, Cruz-Jentoft A et al (2011) Geriatric Care in Europe – the EUGMS Survey part I: Belgium, Czech Republic, Denmark, Germany, Ireland, Spain, Switzerland, United Kingdom. Eur Geriatr Med (EGM) 2:290–295
GEK B (2010) Pflegereport 2010. Asgard, St. Augustin
Hurria A, Wong FL, Villaluna D et al (2008) Role of age and health in treatment recommendations for older adults with breast cancer: the perspective of oncologists and primary care providers. J Clin Oncol 26:5386–5392
Klotz L (2005) Active surveillance for prostate cancer: for whom? J Clin Oncol 23:8165–8169
Klotz L, Vesprini D, Sethukavalan P et al (2015) Long-term follow-up of a large active surveillance cohort of patients with prostate cancer. J Clin Oncol 33:272–277
Kolb G (2009) Versorgungsdichte mit geriatrischer Fachkompetenz in Deutschland. G Kolb für und im Auftrag des Dachverbandes der Gerontologischen und Geriatrischen Gesellschaften Deutschland e. V. (DVGG). Euro J Ger 11:11–13
Kolb G, Rehmann P, Karbe-Voigt N, Wöstmann B (2015) Are old patients not fit for clinical trials, or do clinical trials not fit to old patients? – A survey in 35 pharmaceutical companies. Eur Geriatr Med (EGM) 6:354–357
Kolb G, Breuninger K, Gronemeyer S et al (2014) Ten years of early complex geriatric rehabilitation therapy in the DRG system. Z Gerontol Geriatr 47:6–12
Kolb GF (2002) Malignant diseases in the elderly. The elderly tumor patient. Internist (Berl) 43:959–964
Kornblith AB, Kemeny M, Peterson BL et al (2002) Survey of oncologists‘ perceptions of barriers to accrual of older patients with breast carcinoma to clinical trials. Cancer 95:989–996
Krebsinformationsdienst (2013) Prostatakrebs: Früherkennung, Untersuchung, Behandlung, Nachsorge. Eine Übersicht für Patienten, Interessierte und Fachkreise. Krebsforschungszentrum, Heidelberg
Loeb S, Bjurlin MA, Nicholson J et al (2014) Overdiagnosis and overtreatment of prostate cancer. Eur Urol 65:1046–1055
Monfardini S, Basso U (2007) Oncological causes of frailty in older cancer patients. Eur J Cancer 43:1230–1231
Pallis AG, Wedding U, Lacombe D et al (2010) Questionnaires and instruments for a multidimensional assessment of the older cancer patient: what clinicians need to know? Eur J Cancer 46:1019–1025
Parkin DM, Laara E, Muir CS (1988) Estimates of the worldwide frequency of sixteen major cancers in 1980. Int J Cancer 41:184–197
Simpkin AJ, Tilling K, Martin RM et al (2015) Systematic review and meta-analysis of factors determining change to radical treatment in active surveillance for localized prostate cancer. Eur Urol 67:993–1005
Solomon D, Sue Brown A, Brummel-Smith K et al (2003) Best paper of the 1980s: National Institutes of Health Consensus Development Conference Statement: geriatric assessment methods for clinical decision-making. 1988. J Am Geriatr Soc 51:1490–1494
Soubeyran P, Fonck M, Blanc-Bisson C et al (2012) Predictors of early death risk in older patients treated with first-line chemotherapy for cancer. J Clin Oncol 30:1829–1834
Thomsen FB, Brasso K, Klotz LH et al (2014) Active surveillance for clinically localized prostate cancer – a systematic review. J Surg Oncol 109:830–835
Bergh RC van den, Albertsen PC, Bangma CH et al (2013) Timing of curative treatment for prostate cancer: a systematic review. Eur Urol64:204–215
Vickers AJ, Cronin AM, Bjork T et al (2010) Prostate specific antigen concentration at age 60 and death or metastasis from prostate cancer: case-control study. BMJ 341:4521
Weissbach L, Stuerzebecher S, Mumperow E et al (2015) HAROW: the first comprehensive prospective observational study comparing treatment options in localized prostate cancer. World J Urol (Epub ahead of print)
Haux R, Hein A, Kolb G et al (2014) Information and Communication technologies for promoting and sustaining quality of life, health and self-sufficiency in ageing societies – outcomes of the Lower Saxony Research Network Design of Environments for Ageing (GAL). Inform Health Soc Care 39(3–4):166–187
Einhaltung ethischer Richtlinien
Interessenkonflikt. G. Kolb und L. Weißbach geben an, dass kein Interessenkonflikt besteht. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kolb, G., Weißbach, L. Demografischer Wandel. Urologe 54, 1701–1709 (2015). https://doi.org/10.1007/s00120-015-4004-z
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00120-015-4004-z