Skip to main content
Log in

Der akute Thoraxschmerz, ein rein klinisches Problem oder radiologische Fragestellung?

Acute chest pain: a purely clinical problem or a question for radiology?

  • Leitthema
  • Published:
Der Radiologe Aims and scope Submit manuscript

Zusammenfassung

Der akute Thoraxschmerz repräsentiert ein sehr häufiges klinisches Beschwerdebild und gleichzeitig ein großes diagnostisches Dilemma, können sich doch sowohl lebensbedrohliche akute Ereignisse (wie der akute Herzinfarkt) als auch mehr oder weniger harmlose Schmerzzustände und Erkrankungen (wie vertebrogene Schmerzen) unter dem Leitsymptom „akuter Thoraxschmerz“ präsentieren. Diese oft nicht eindeutige Symptomatik, hinter der immer auch ein lebensbedrohliches Krankheitsbild stecken kann, führt zu einer Übertriagierung der Patienten in Notaufnahmen und zu einer großen Anzahl an stationären „Absicherungsaufnahmen“. Besonders die Diagnose eines akuten Koronarsyndroms (AKS) bei initial fehlenden ischämietypischen EKG-Veränderungen stellt eine spezielle Problematik dar. Durch die Verfügbarkeit moderner ultraschneller Multidetektorcomputertomographen (MDCT) spielt der Radiologe in der Diagnostik und Abklärung des akuten Thoraxschmerzes eine zunehmend wichtige Rolle. Im Folgenden sollen die klinischen Schwierigkeiten und radiologischen Möglichkeiten der Diagnose von Patienten mit akutem Thoraxschmerz vorgestellt und mögliche zukünftige Diagnosealgorithmen diskutiert werden.

Abstract

Acute chest pain represents a very common clinical occurrence and at the same time poses a severe diagnostic dilemma. It can be due to an acute life-threatening event such as acute cardiac infarct, or a relatively harmless condition of pain and illness (e.g. vertebrogenic pain) under the main symptom category of acute chest pain. This often unclear symptomatic, behind which there can always be a life-threatening disease leads to an exaggerated grouping of patients into emergency cases and to an increased number of inpatients for observation. The diagnosis of acute coronary syndrome with no initial ECG changes typical for ischemia is especially problematic. The availability of modern multidetector computed tomography is becoming increasingly more important for radiologists in the diagnosis and clarification of acute chest pain. In this article the clinical difficulties and radiology options for the diagnosis of patients with acute chest pain will be presented and possible future algorithms for diagnosis will be discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Abb. 1
Abb. 2
Abb. 3
Abb. 4

Literatur

  1. Anderson JL, Adams CD, Antman EM et al. (2007) ACC/AHA Guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction. JACC 50: e1–e157

    PubMed  Google Scholar 

  2. Antman EM, Anbe DT, Armstrong PW (2004) ACC/AHA Guidelines for the management of patients with ST-elevation myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (Committee to revise the 1999 Guidelines for the Management of Patients With Acute Myocardial Infarction). Developed in collaboration with the Canadian Cardiovascular Society. ACC/AHA Practice Guidelines. Access: http://www.acc.org/qualityandscience/clinical/guidelines/stemi/STEMI%20Full%20Text.pdf

  3. Fineberg HV, Scadden D, Goldman L (1984) Care of patients with a low probability of acute myocardial infarction. Cost effectiveness of alternatives to coronary-care-unit admission. N Engl J Med 310: 1301–1307

    PubMed  CAS  Google Scholar 

  4. Gallagher MJ, Ross MA et al. (2007) The diagnostic accuracy of 64-slice computed tomography coronary angiography compared with stress nuclear imaging in emergency department low-risk chest pain patients. Ann Emerg Med 49: 125–136

    Article  PubMed  Google Scholar 

  5. Goldstein JA, Gallagher MJ et al. (2007) A randomized controlled trial of multi-slice coronary computed tomography for evaluation of acute chest pain. J Am Coll Cardiol 49: 863–871

    Article  PubMed  Google Scholar 

  6. Hacker M, Jakobs T et al. (2007) Sixty-four slice spiral CT angiography does not predict the functional relevance of coronary artery stenoses in patients with stable angina. Eur J Nucl Med Mol Imaging 34: 4–10

    Article  PubMed  Google Scholar 

  7. Hoffmann U, Pena AJ et al. (2006) MDCT in early triage of patients with acute chest pain. AJR Am J Roentgenol 187: 1240–1247

    Article  PubMed  Google Scholar 

  8. Hoffmann U, Nagurney JT et al. (2006) Coronary multidetector computed tomography in the assessment of patients with acute chest pain. Circulation 114: 2251–2260

    Article  PubMed  Google Scholar 

  9. Husmann L, Valenta I et al. (2007) Feasibility of low-dose coronary CT angiography: first experience with prospective ECG-gating. Eur Heart J Dec 18 Epub ahead of print

  10. Kaul P, Newby LK, Fu Y et al (2004) International differences in evolution of early discharge after acute myocardial infarction. Lancet 363: 511–517

    Article  PubMed  Google Scholar 

  11. Khan IA, Nair CK (2002) Clinical, diagnostic, and management perspectives of aortic dissections. Chest 122: 311–328

    Article  PubMed  Google Scholar 

  12. Leber AW, Knez A et al. (2005) Quantification of obstructive and nonobstructive coronary lesions by 64-slice computed tomography: a comparative study with quantitative coronary angiography and intravascular ultrasound. J Am Coll Cardiol 46: 147–154

    Article  PubMed  Google Scholar 

  13. Lee TH, Goldman L (2000) Evaluation of patients with acute chest pain. N Engl J Med 342: 1187–1195

    Article  PubMed  CAS  Google Scholar 

  14. Leschka S, Alkadhi H et al. (2005) Accuracy of MSCT coronary angiography with 64-slice technology: first experience. Eur Heart J 26: 1482–1487

    Article  PubMed  Google Scholar 

  15. McCaig LF, Burt CW (2004) National Hospital Ambulatory Medical Care Survey: 2002 emergency department summary. Adv Data 340: 1–34

    PubMed  Google Scholar 

  16. Mollet NR, Cademartiri F et al. (2005) High-resolution spiral computed tomography coronary angiography in patients referred for diagnostic conventional coronary angiography. Circulation 112: 2318–2323

    Article  PubMed  Google Scholar 

  17. Morion RL, Gerber TC, McCollough CH (2003) Radiation dose in computed tomography of the heart. Circulation 107: 917–922

    Article  Google Scholar 

  18. Pope JH, Aufderheide TP, Ruthazer R et al. (2000) Missed diagnoses of acute cardiac ischemia in the emergency department. N Engl J Med 342: 1163–1170

    Article  PubMed  CAS  Google Scholar 

  19. Pozen MW, D’Agostino RB, Selker HP et al. (1984) A predictive instrument to improve coronary-care-unit admission practices in acute ischemic heart disease. A prospective multicenter clinical trial. N Engl J Med 310: 1273–1278

    PubMed  CAS  Google Scholar 

  20. Remy-Jardin M, Pistolesi M et al. (2007) Management of suspected acute pulmonary embolism in the era of CT angiography: a statement from the Fleischner Society. Radiology 245: 315–329

    Article  PubMed  Google Scholar 

  21. Roe MT, Harrington RA, Prosper DM et al. (2000) Clinical and therapeutic profile of patients presenting with acute coronary syndromes who do not have significant coronary artery disease. The platelet glycoprotein IIb/IIIa in unstable angina: Receptor Suppression Using Integrilin Therapy (PURSUIT) Trial Investigators. Circulation102: 1101–1106

  22. Rubinshtein R, Halon DA et al. (2007) Usefulness of 64-slice cardiac computed tomographic angiography for diagnosing acute coronary syndromes and predicting clinical outcome in emergency department patients with chest pain of uncertain origin. Circulation115: 1762–1768

  23. Selker HP, Zalenski RJ, Antmann EM et al. (1997) An evaluation of technologies for identifying acute cardiac ischemia in the emergency department: a report from a National Heart Attack Alert program Working Group. Ann Emerg Med 29: 13–87

    Article  PubMed  CAS  Google Scholar 

  24. Stein PD, Beemath A et al. (2007) Usefulness of multidetector spiral computed tomography according to age and gender for diagnosis of acute pulmonary embolism. Am J Cardiol 99: 1303–1305

    Article  PubMed  Google Scholar 

  25. Stillman AE, Oudkerk M, Ackerman M (2007) Use of multidetector computed tomography for the assessment of acute chest pain: a consensus statement of the North American Society of Cardiac Imaging and the European Society of Cardiac Radiology. Eur Radiol 17: 2196–2207

    Article  PubMed  Google Scholar 

  26. Svensson LG, Labib SB, Eisenhauer AC et al. (1999) Intimal tear without hematoma: an important variant of aortic dissection that can eldue current imaging techniques. Circulation 99: 1331–1336

    PubMed  CAS  Google Scholar 

  27. Wallentin L, Lagerqvist B, Husted S et al. (2000) Outcome at 1 year after an invasive compared with a non-invasive strategy in unstable coronary-artery disease: the FRISC II invasive randomised trial. FRISC II Investigators. Fast revascularisation during instability in coronary artery disease. Lancet 356(9223): 9–16

    Article  PubMed  CAS  Google Scholar 

  28. Wells PS, Anderson DR, Rodger M et al. (2000) Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpleRED D-dimer. Thromb Haemost 8: 416–420

    Google Scholar 

Download references

Interessenkonflikt

Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to C. Loewe.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Loewe, C. Der akute Thoraxschmerz, ein rein klinisches Problem oder radiologische Fragestellung?. Radiologe 48, 448–456 (2008). https://doi.org/10.1007/s00117-008-1656-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00117-008-1656-3

Schlüsselwörter

Keywords

Navigation