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Neue SEPSIS-3-Definition

Müssen wir Sepsis in Zukunft behandeln, bevor wir sie diagnostizieren dürfen?

New Sepsis-3 definition

Do we have to treat sepsis before we can diagnose it from now on?

  • Intensivmedizin
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Zusammenfassung

Seit Anfang 2016 gibt es die „dritten internationalen Konsensusdefinitionen“ für Sepsis und septischen Schock (SEPSIS-3, engl. The Third International Consensus Definitions for Sepsis and Septic Shock). SEPSIS-3 schafft dabei die alten SIRS-Kriterien in der Definition der Sepsis als Ganzes ab und definiert die Sepsis in Zukunft alleine durch eine „lebensbedrohliche Organdysfunktion auf dem Boden einer Infektion“. Allerdings erscheint zweifelhaft, ob die neue Definition der alten im klinischen Alltag wirklich überlegen ist. Die wichtigste Frage dabei: Ist eine Definition hilfreich, die Patienten erst erkennt, wenn die Organdysfunktion eingetreten ist und die Patienten bereits intensivpflichtig sind?

Abstract

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) have been available since the beginning of 2016. SEPSIS-3 completely replaces the old SIRS criteria in the definition of sepsis and defines sepsis from now on as “life-threatening organ dysfunction caused by a dysregulated host response to infection”. However, it seems questionable whether in clinical practice the new definition is really superior to the old one. The most important question is the following: Is it helpful to have a definition that first recognizes a patient once organ dysfunction has occurred and the patient already needs intensive care?

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Authors and Affiliations

  1. Klinik für Anästhesiologie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland

    T. Schmoch, F. Uhle, T. Brenner & M. A. Weigand

  2. Zentrale Notaufnahme, Universitätsklinikum Leipzig AöR, Leipzig, Deutschland

    M. Bernhard

  3. Klinik für Anästhesiologie, Universitätsmedizin Greifswald, Greifswald, Deutschland

    M. Gründling

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  1. T. Schmoch
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  2. M. Bernhard
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  3. F. Uhle
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  4. M. Gründling
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  5. T. Brenner
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Correspondence to T. Schmoch.

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Interessenkonflikt

T. Schmoch, M. Bernhard, F. Uhle, M. T. Gründling, T. Brenner und M.A. Weigand geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

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Schmoch, T., Bernhard, M., Uhle, F. et al. Neue SEPSIS-3-Definition. Anaesthesist 66, 614–621 (2017). https://doi.org/10.1007/s00101-017-0316-2

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