Zusammenfassung
Maligne Tumoren der Haut sind die häufigste Krebsart des Menschen. Basalzellkarzinome werden in einem anderen Kapitel abgehandelt (Kap. „Basalzellkarzinom“), während die weiteren epithelialen malignen Tumoren hier betrachtet werden. Die Ursachen von Hautkrebs sind vielfältig und umfassen genetische Faktoren, wie beispielsweise eine herabgesetzte DNA-Reparaturkapazität, exogene kanzerogene Faktoren (überwiegend UV-Bestrahlung), aber auch verschiedene humane Papillomviren (HPV), chemische Karzinogene, ionisierende Strahlen und Immunsuppression. Individuelle Faktoren, wie etwa Hautfarbe, Dicke des Stratum corneum, Immunstatus oder chronisch entzündliche Erkrankungen der Haut, können weitere Risikofaktoren sein.
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Sterry, W., Stockfleth, E. (2018). Maligne epitheliale Tumoren. In: Plewig, G., Ruzicka, T., Kaufmann, R., Hertl, M. (eds) Braun-Falco’s Dermatologie, Venerologie und Allergologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49544-5_102
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