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Erschienen in:

2025 | OriginalPaper | Buchkapitel

13. Fetale Tumoren

verfasst von : Prof. Dr. med. Annegret Geipel

Erschienen in: Ultraschalldiagnostik in Geburtshilfe und Gynäkologie

Verlag: Springer Berlin Heidelberg

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Zusammenfassung

Kongenitale Tumoren sind selten. Sie stellen in der Regel benigne Läsionen dar. Die Raumforderungen können überwiegend zystisch, solide oder eine Mischform aus beiden sein. Die pränatale Diagnose erfolgt meist im späten II. oder III. Trimester. Die Einteilung erfolgt nach Lokalisation und vermuteter histologischer Diagnose. Lymphangiome und Teratome sind pränatal die am häufigsten anzutreffenden Tumore. Die pränatale Diagnose eines fetalen Tumors erlaubt die interdisziplinäre Betreuung und Beratung der Schwangeren, die engmaschigere Überwachung der Schwangerschaft sowie die Optimierung des geburtshilflichen Managements. Dies kann zu einer Verbesserung des kindlichen Outcomes beitragen.

Vorheriges Kapitel Skelettsystem

Nächstes Kapitel Pathologische Plazenta und Nabelschnur

Altmann RP, Randolph JG, Lilly JR (1974) Sacrococcygeal teratoma: American Academy of Pediatrics Surgical Sectior 1973. J Pediatr Surg 9:389–398CrossRef

Arisoy R, Erdogdu E, Kumru P, Demirci O, Ergin N, Pekin O, Sahinoglu Z, Tugrul AS, Sancak S, Çetiner H, Celayir A (2016) Prenatal diagnosis and outcomes of fetal teratomas. J Clin Ultrasound 44:118–125PubMedCrossRef

Barksdale EM Jr, Obokhare I (2009) Teratomas in infants and children. Curr Opin Pediatr 21:334–349CrossRef

Bascietto F, Liberati M, Marrone L, Khalil A, Pagani G, Gustapane S, Leombroni M, Buca D, Flacco ME, Rizzo G, Acharya G, Manzoli L, D’Antonio F (2017) Outcome of fetal ovarian cysts diagnosed on prenatal ultrasound examination: systematic review and meta-analysis. Ultrasound Obstet Gynecol 50:20–31PubMedCrossRef

Bedei IA, Huisman TAGM, Whitehead W, Axt-Fliedner R, Belfort M, Sanz Cortes M (2022) Fetal brain tumors, a challenge in prenatal diagnosis, counselling, and therapy. J Clin Med 12:58PubMedPubMedCentralCrossRef

Birkemeier KL (2020) Imaging of solid congenital abdominal masses: a review of the literature and practical approach to image interpretation. Pediatr Radiol 50:1907–1920PubMedCrossRef

Catania VD, Briganti V, Di Giacomo V, Miele V, Signore F, de Waure C, Calabrò GE, Calisti A (2016) Fetal intra-abdominal cysts: accuracy and predictive value of prenatal ultrasound. J Matern Fetal Neonatal Med 29:1691–1699PubMedCrossRef

Cavalheiro S, da Costa MDS, Richtmann R (2021) Everolimus as a possible prenatal treatment of in utero diagnosed subependymal lesions in tuberous sclerosis complex: a case report. Childs Nerv Syst 37:3897–3899PubMedCrossRef

Chao AS, Chao A, Wang TH, Chang YC, Chang YL, Hsieh CC, Lien R, Su WJ (2008) Outcome of antenatally diagnosed cardiac rhabdomyoma: case series and a meta- analysis. Ultrasound Obstet Gynecol 31:289–295PubMedCrossRef

Chen J, Wang J, Sun H, Gu X, Hao X, Fu Y, Zhang Y, Liu X, Zhang H, Han L, He Y (2019) Fetal cardiac tumor: echocardiography, clinical outcome and genetic analysis in 53 cases. Ultrasound Obstet Gynecol 54:103–109PubMedCrossRef

Cho JY, Lee YH (2014) Fetal tumors: prenatal ultrasonographic findings and clinical characteristics. Ultrasonography 33:240–251PubMedPubMedCentralCrossRef

Choudhry S, Nguyen HH, Anwar S (2015) Rapid resolution of cardiac rhabdomyomas following everolimus therapy. BMJ Case Rep 2015:bcr2015212946PubMedPubMedCentralCrossRef

Cornejo P, Feygin T, Vaughn J, Pfeifer CM, Korostyshevska A, Patel M, Bardo DME, Miller J, Goncalves LF (2020) Imaging of fetal brain tumors. Pediatr Radiol 50:1959–1973PubMedCrossRef

Davidson JR, Uus A, Matthew J, Egloff AM, Deprez M, Yardley I, De Coppi P, David A, Carmichael J, Rutherford MA (2021) Fetal body MRI and its application to fetal and neonatal treatment: an illustrative review. Lancet Child Adolesc Health 5:447–458PubMedPubMedCentralCrossRef

Dimitraki M, Koutlaki N, Nikas I, Mandratzi T, Gourovanidis V, Kontomanolis E, Zervoudis S, Galazios G, Liberis V (2012) Fetal ovarian cysts. Our clinical experience over 16 cases and review of the literature. J Matern Fetal Neonatal Med 25:222–225PubMedCrossRef

Ercan F, Sarikaya M, Toprak E, Findik S, Arbag H, Acar A (2018) Prenatal diagnosis and intrapartum management of congenital ranula. Z Geburtsh Neonatol 222:262–265CrossRef

Faschingbauer F, Geipel A (2017) Fetale und plazentare Tumore. In: Berg C (Hrsg) Fetale Therapie. De Gruyter, Berlin Boston, S 273–300CrossRef

Feygin T, Khalek N, Moldenhauer JS (2020) Fetal brain, head, and neck tumors: prenatal imaging and management. Prenat Diagn 40:1203–1219PubMedCrossRef

García-Díaz L, Chimenea A, de Agustín JC, Pavón A, Antiñolo G (2020) Ex-Utero Intrapartum Treatment (EXIT): indications and outcome in fetal cervical and oropharyngeal masses. BMC Pregnancy Childbirth 20:598PubMedPubMedCentralCrossRef

Geurten C, Geurten M, Rigo V, Dresse MF (2020) Neonatal cancer epidemiology and uutcome: a retrospective study. J Pediatr Hematol Oncol 42:e286–e292PubMedCrossRef

Goergen SK, Fahey MC (2022) Prenatal MR imaging phenotype of fetuses with tuberous sclerosis: an institutional case series and literature review. Am J Neuroradiol 43:633–638PubMedPubMedCentralCrossRef

Gucciardo L, Uyttebroek A, De Wever I, Renard M, Claus F, Devlieger R, Lewi L, De Catte L, Deprest J (2011) Prenatal assessment and management of sacrococcygeal teratoma. Prenat Diagn 31:678–688PubMedCrossRef

Guerre M, Boehnlein C, Sohaey R, Seideman CA (2022) Imaging of prenatal and neonatal intra-abdominal genitourinary tumors: a review of the literature. Curr Urol Rep 23:39–46PubMedCrossRef

Isaacs H (2007) Fetal and neonatal hepatic tumors. J Pediatr Surg 42:1797–1803PubMedCrossRef

Isaacs H (2009) Fetal brain tumors: a review of 154 cases. Am J Perinatol 26:607–612CrossRef

Johnson AB, Richter GT (2018) Vascular anomalies. Clin Perinatol 45:737–749PubMedCrossRef

Kamil D, Tepelmann J, Berg C, Heep A, Axt-Fliedner R, Gembruch U, Geipel A (2008) Spectrum and outcome of prenatally diagnosed fetal tumors. Ultrasound Obstet Gynecol 31:296–302PubMedCrossRef

Knipping S, Bau V (2011) Lymphatische Malformationen im Kopf-Hals-Bereich. Erfahrungen mit Sklerosierungstherapie. HNO 59:683–688PubMedCrossRef

Kops AL, Hulsker CC, Fiocco M, Zsiros J, Mavinkurve-Groothuis AMC, Looijenga LH, van der Steeg AF, Wijnen MH (2020) Malignant recurrence after mature sacrococcygeal teratoma: a meta-analysis and review of the literature. Crit Rev Oncol Hematol 156:103140PubMedCrossRef

Lakhoo K, Sowerbutts H (2010) Neonatal tumours. Pediatr Surg Int 26:1159–1168PubMedCrossRef

Li JL, Hai-Ying W, Liu JR, He QM, Chen KS, Yang J, Qian F (2018) Fetal Lymphangioma: prenatal diagnosis on ultrasound, treatment, and prognosis. Eur J Obstet Gynecol Reprod Biol 231:268–273PubMedCrossRef

Liao M, He B, Xiao Z, Wang L, Chen Y, Liu X, Shu S, Shang N (2023) Prenatal ultrasound evaluation of fetal cutaneous hemangioma and related complications. J Matern Fetal Neonatal Med 36:2157257PubMedCrossRef

López-Gutiérrez JC (2019) Clinical and economic impact of surgery for treating infantile hemangiomas in the era of propranolol: overview of single-center experience from La Paz Hospital, Madrid. Eur J Pediatr 178:1–6PubMedCrossRef

Meizner I (2000) Perinatal oncology – the role of prenatal ultrasound diagnosis. Ultrasound Obstet Gynecol 16:507–509PubMedCrossRef

Mettling K, Murcek K, Rubarth LB (2013) Malignancies and tumors in the neonate. Neonatal Netw 32:34–40PubMedCrossRef

Mikovic Z, Simic R, Egic A, Opincal TS, Koprivsek K, Stanojevic D, Bogavac M, Popovac M, Mandic V. (2009) Intrauterine treatment of large fetal neck lymphangioma with OK-432. Fetal Diagn Ther. 26:102–106.PubMedCrossRef

Nassr AA, Shazly SA, Morris SA, Ayres N, Espinoza J, Erfani H, Olutoye OA, Sexson SK, Olutoye OO, Fraser CD Jr, Belfort MA, Shamshirsaz AA (2017) Prenatal management of fetal intrapericardial teratoma: a systematic review. Prenat Diagn 37:849–863PubMedCrossRef

Olsen GM, Nackers A, Drolet BA (2020) Infantile and congenital hemangiomas. Semin Pediatr Surg 29:150969PubMedCrossRef

Pongsatha S, Jatavan P, Hantrakun P, Tongsong T (2023) Prenatal detection of rapid progressive changes in massive lymphangioma from flank to the lower extremity. Diagnostics 13:2130PubMedPubMedCentralCrossRef

Salim A, Raitio A, Losty PD (2023) Long-term functional outcomes of sacrococcygeal teratoma - A systematic review of published studies exploring ‘real world’ outcomes. Eur J Surg Oncol 49:16–20PubMedCrossRef

Sepulveda W, Sepulveda F, Corral E, Gutierrez J (2021) Giant hepatic hemangioma in the fetus: case reports and updated review of the literature. J Matern Fetal Neonatal Med 34:2554–2566PubMedCrossRef

Sharma D, Subbarao G, Saxena R (2017) Hepatoblastoma. Semin Diagn Pathol 34:192–200PubMedCrossRef

Sugimoto M, Kurishima C, Masutani S, Tamura M, Senzaki H (2015) Congenital brain tumor within the first 2 months of life. Pediatr Neonatol 56:369–375PubMedCrossRef

Takahashi H, Ohkuchi A, Kuwata T, Usui R, Takahashi S, Matsubara S (2015) Congenital mesoblastic nephroma: Its diverse clinical features. A literature review with a case report. J Obstet Gynaecol 14:1–5

Tripathy PK, Jena PK, Pattnaik K (2022) Management outcomes of mesenteric cysts in paediatric age group. Afr J Paediatr Surg 19:32–35PubMedCrossRef

Tyraskis A, Bakalis S, David AL, Eaton S, De Coppi P (2017) A systematic review and meta-analysis on fetal ovarian cysts: impact of size, appearance and prenatal aspiration. Prenat Diagn 37:951–958PubMedCrossRef

Van Mieghem T, Al-Ibrahim A, Deprest J, Lewi L, Langer JC, Baud D, O’Brien K, Beecroft R, Chaturvedi R, Jaeggi E, Fish J, Ryan G (2014) Minimally invasive therapy for fetal sacrococcygeal teratoma: case series and systematic review of the literature. Ultrasound Obstet Gynecol 43:611–619PubMedCrossRef

Yuan SM (2017) Fetal primary cardiac tumors during perinatal period. Pediatr Neonatol 58:205–210PubMedCrossRef

Titel: Fetale Tumoren
verfasst von: Prof. Dr. med. Annegret Geipel
Verlag: Springer Berlin Heidelberg
Buch: Ultraschalldiagnostik in Geburtshilfe und Gynäkologie
Print ISBN: 978-3-662-67372-0

Electronic ISBN: 978-3-662-67373-7

Copyright-Jahr: 2025
DOI: https://doi.org/10.1007/978-3-662-67373-7_13

Springerpflege

Zusammenfassung

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