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Erschienen in: Zeitschrift für Gerontologie und Geriatrie 3/2017

01.04.2017 | Original Contribution

Erythrocyte rheological properties but not whole blood and plasma viscosity are associated with severity of hypertension in older people

verfasst von: Guo-xiang Fu, Min Ji, Li-zhi Han, Chan-chan Xu, Feng-feng Pan, Ting-jun Hu, Yuan Zhong

Erschienen in: Zeitschrift für Gerontologie und Geriatrie | Ausgabe 3/2017

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Abstract

Objective

This study was carried out to determine whether changes in hemorheological parameters parallel the severity of essential hypertension.

Methods

A total of 198 older hypertensive patients were recruited and classified into 3 stages of hypertension according to the grading standard of hypertension. The whole blood viscosity (WBV) at various shear rates, plasma viscosity and erythrocyte rheology (including erythrocyte rigidity index, erythrocyte aggregation index and erythrocyte deformation index) were examined.

Results

Erythrocyte rheology paralleled the severity of essential hypertension and was significantly correlated to the average 24 h systolic blood pressure and diastolic blood pressure. Logistic analysis revealed that erythrocyte rigidity and the erythrocyte aggregation index were positively correlated with the severity of hypertension, while the erythrocyte deformation index was negatively correlated. No association was found between WBV, plasma viscosity and the severity of hypertension.

Conclusion

The rheological properties of erythrocyte viscosity were correlated with the severity of hypertension in older people but the WBV and plasma viscosity were not.
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Metadaten
Titel
Erythrocyte rheological properties but not whole blood and plasma viscosity are associated with severity of hypertension in older people
verfasst von
Guo-xiang Fu
Min Ji
Li-zhi Han
Chan-chan Xu
Feng-feng Pan
Ting-jun Hu
Yuan Zhong
Publikationsdatum
01.04.2017
Verlag
Springer Medizin
Erschienen in
Zeitschrift für Gerontologie und Geriatrie / Ausgabe 3/2017
Print ISSN: 0948-6704
Elektronische ISSN: 1435-1269
DOI
https://doi.org/10.1007/s00391-016-1039-8