Weitere Artikel dieser Ausgabe durch Wischen aufrufen
A correlation between asymmetry in electroencephalographs (EEG) and depression has been demonstrated in many studies. To the best of our knowledge there are no studies including oldest old geriatric patients.
The objective of this study was to evaluate whether frontal and parietal alpha asymmetry can be used to differentiate between depressed and control patients in a cohort sample with a mean age of 80 years.
Differences in the EEG were investigated in 39 right-handed female geriatric patients (mean age 80 years) with respect to frontal alpha asymmetry (FAA) and parietal alpha asymmetry (PAA) in depression (n = 14), depression combined with anxiety (n = 11) and normal controls (n = 14) as assessed with the hospital anxiety and depression scale (HADS). Band power was calculated for alpha 1 (6.9–8.9 Hz), alpha 2 (8.9–10.9 Hz) and alpha 3 bands (10.9–12.9 Hz). Furthermore, correlations between frontal and parietal alpha asymmetry and the geriatric depression scale (GDS), the HADS and the mini mental state examination (MMSE) were calculated.
A differentiation between the three groups was not possible with FAA and PAA. Significant correlations were found between PAA alpha 3 band and anxiety and depression.
The alpha asymmetry in EEG seemed to disappear with age. Correlations between PAA and anxiety and depression were found. The results are in line with the right (hemisphere) hemi-aging hypothesis.
Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten
Sie möchten Zugang zu diesem Inhalt erhalten? Dann informieren Sie sich jetzt über unsere Produkte:
Chandler MJ, Lacritz LH, Hynan LS, Barnard HD, Allen G, Deschner M, Weiner MF, Cullum CM (2005) A total score for the CERAD neuropsychological battery. Neurology. doi:10.1212/01.wnl.0000167607.63000.38 PubMed
Morris JC, Mosh RC, Rogers H, Fillenbaum G, Heyman A (1988) Consortium to establish a registry for alzheimer’s disease. Psychopharmacol Bull 24:641–652 PubMed
Quinn CR, Rennie CJ, Harris AWF, Kemp AH (2013) The impact of melancholia versus non-melancholia on resting-state, EEG alpha asymmetry: Electrophysiological evidence for depression heterogeneity. Psychiatry Res. doi:10.1016/j.psychres.2013.12.049
Schaffer CE, Davidson RJ, Saron C (1983) Frontal and parietal electroencephalogram asymmetry in depressed and nondepressed subjects. Biol Psychiatry 18:753–762 PubMed
Sheikh JI, Yesavage JA (1986) Geriatric Depression Scale (GDS). Recent evidence and development of a shorter version. In: Brink TL (ed) Clinical Gerontology: a Guide to Assessment and Intervention. Haworth Press, NY, pp 165–173
Electroencephalogram alpha asymmetry in geriatric depression
Valid or vanished?
Andreas K. Kaiser
- Springer Medizin
Zeitschrift für Gerontologie und Geriatrie
Print ISSN: 0948-6704
Elektronische ISSN: 1435-1269